Ekos Corporation

Boston Scientific Scimed, Inc.

The General Hospital Corporation

Adrian F Prokop

Azita Soltani

William P Wiesmann

Jill Uyeno

Adrian Richard Urias

Jason Milne

Kristopher Jarka

Farbod Ghassemi

In one embodiment of the present invention, a system for treating an occlusion within a patient's vasculature with ultrasonic energy comprises a catheter configured to be passed through the patient's vasculature such that a portion of the catheter is positioned at an intravascular treatment site. The system further comprises an ultrasound radiating member, an ultrasound signal generator configured to supply a drive signal to the ultrasound radiating member, an infusion pump configured to pump a therapeutic compound into the fluid delivery lumen so as to cause the therapeutic compound to be delivered to the treatment site and a controller configured to control the ultrasound signal generator and the infusion pump.

Ultrasound therapy system

A system for assessing organ function couples light emitters into an optical fiber delivery assembly of which the tip extends to or into an internal organ and illuminates tissue; the device senses temperature at the tip, and a collection fiber collects light scattered, reflected or emitted by the surrounding tissue. Control and processing modules drive the laser diodes and process return spectral signals, e.g., to assess metabolic activity and detect onset of shock. A prototype uses four laser diodes with peaks at 735, 760, 805 and 890 nm, with a front end splitter providing a reference beam to a photo detector for normalizing detection output and correcting the signal samples. The device may include a plurality of laser diodes and may select subsets of the sources to tailor spectral illumination to different target enzymes, metabolites or other compounds. The processor may include heuristic correlators for interpreting the physiological state or detecting the onset of shock based on magnitudes of multiple different measured parameters.

Minimally invasive system for assessment of organ function

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Seattle, WA, United States of America

Adrian F Prokop