Warner-Lambert Company

Boehringer Ingelheim Kg

Godecke Aktiengesellschaft

Adolf Knecht

Michael Schneider

Helmut Augart

Hans-Hermann Weil

Ottfried Daab

Uwe Gebhardt

Gerhard Sluke

Robert Roos

Peter Grass

Klaus Arnold

Joachim Wenzel

Herbet Thieme

Powders for inhalation

A metering valve for a pressurized dispensing container. The container is intended to operate in the inverted position. An element having a raised peripheral portion is provided about the valve housing which substantially closes the space between the wall of the container and the valve housing. The element prevents the settling of active substances of the material being dispensed in the region of the inlet opening of the metering valve.

Sediment baffle for valves of pressurized containers

A process for the preparation of an antacid material prepared from magnesium aluminum hydroxide, wherein magnesium hydroxide and/or magnesium oxide is reacted in an atomic ratio of magnesium to aluminum of 1:1 to 3:1 with an aqueous solution of aluminum sulfate until the pH of the reaction mixture is from 4.0 to 8.0, whereafter water-soluble components are removed from the mixture is known manner and this is isolated and, if desired, dried is described as well as a new embodiment of the formula [Mg.sub.5 Al.sub.10 (OH).sub.26 O.sub.5 ](SO.sub.4).sub.2 .multidot.nH.sub.2 O. Also described are pharmaceutical compositions containing such antacid material, in admixture with a conventional pharmaceutical adjuvant, and a method of combating hyperacidity and gastrointestinal diseases, which comprises administering such antacid material.

Antacid material

Antirheumatically active suppositories with comparable bioavailability to oral or parenteral preparations are described, which contain a salt of a compound of general Formula I ##STR1## in which R.sup.1 represents a heterocyclic ring and X together with Y an annelated aromatic ring; and an organic base of the general Formula II

Antirheumatically active suppositories

The present invention provides a process for the timed control of the liberation of active material from a retarded active material-containing composition by the addition of a hydrophilic polymer, wherein the rate of liberation is adjusted by means of the viscosity of the added hydrophilic polymer, the rate of liberation increasing with increasing viscosity.

Process for time-controlled release of active ingredients

The present invention provides a process for the preparation of an antacid material based upon magnesium aluminium hydroxide, wherein magnesium hydroxide and/or magnesium oxide is reacted in an atomic ratio of magnesium to aluminium of 1:1 to 3:1 with an aqueous solution of aluminium sulphate until the pH of the reaction mixture is from 4.0 to 8.0, whereafter water-soluble components are removed from the mixture in known manner and this is isolated and, if desired, dried. The present invention also provides pharmaceutical compositions containing an antacid material prepared by this process, in admixture with a conventional pharmaceutical adjuvant. Furthermore, the present invention provides a method of combating hyperacidity and gastrointestinal diseases, which comprises administering an antacid material prepared by the above process.

Antacid material based on magnesium aluminium hydroxide and the

The present invention provides a pharmaceutical composition containing at least one oxicam derivative of the general formula: ##STR1## in which R is a heterocyclic ring and X together with Y represent a condensed aromatic ring, together with a more than equimolar amount of an organic base of the general formula:

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Freiburg, Germany

Adolf Knecht