Dsm IP Assets B.v.

Adolf Fritz Volker Wagner

Peter Jan Leonard Mario Quaedflieg

Theodorus Sonke

Process for the preparation of a compound with enhanced optical purity wherein a mixture of the enantiomers of a chiral compound of formula 1wherein: Preferably the peptide deformylase is chosen from the class EC 3.5.2.27 or EC 3.5.1.31, and contains the sequences of (I) HEXXH, (ii) EGCLS and (iii) GXGXAAXQ. The bivalent metal may be chosen from the group of Fe, Ni, Mn and Co, preferably Ni or Fe.

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Ludwigsburg, Germany

Adolf Fritz Volker Wagner