Hoffmann-la Roche Inc.

Adeline Boillon

Hanns-Christian Mahler

Michael Adler

Joerg Luemkemann

Tim Dreckmann

Denis Luthringer

Anke Dorn

Alexander Meyer

Karoline Bechthold-peters

Karoline Bechtold-Peters

Andreas Ernst

A dosing system for transferring an aseptic fluid in dosages into a container, comprising a peristaltic pump configured such that the filling accuracy for fill volumes of the aseptic fluid<100 μL is ±3 μL.

Microdosing

A peristaltic dosing device for providing dosages of a fluid at a volume of less than one milliliter comprises: a flexible tube, a counter pressure element, a plurality of actors and a drive. The flexible tube is essentially straightly arranged along the counter pressure element thereby forming a longitudinal axis. The actors arranged parallel to each other along the longitudinal axis. They are moveable by the drive in relation to the flexible tube. The flexible tube is compressible between the actors and the counter pressure element by moving the actors. Each of the actors is independently and linearly moveable by the drive along an actuation axis essentially perpendicular to the longitudinal axis of the flexible tube from a home position in which the flexible tube is least compressed to an end position in which the flexible tube is compressed and sealed between the respective actor and the counter pressure element. The peristaltic dosing device according to the invention allows for exactly and repeatably providing dosages at comparably small volumes in a sterile environment.

Dosing a fluid at a volume of less than one milliliter

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Grasswil, Switzerland

Adeline Boillon