Immunex Corporation

Adel Youakim

Peter Robert Baum

William C Fanslow, Iii

Steven R Wiley

Timothy A Bird

Robert F DuBose

Timothy E Lofton

Eric A Sorensen

This invention relates to new members of the human Claudin polypeptide family, to methods of making such polypeptides, and to methods of using them to treat Claudin-associated conditions and to identify agents that alter Claudin polypeptide activities.

Claudin polypeptides, polynucleotides, and methods of making and use thereof

This invention relates to new members of the human Claudin polypeptide family, to methods of making such polypeptides, and to methods of using them to treat Claudin-associated conditions and to identify compounds that alter Claudin polypeptide activities.

Claudin polypeptides

This invention relates to nectin polypeptides and polynucleotides, to methods of making such polypeptides and polynucleotides, and to methods of using such polypeptides and polynucleotides to modulate cell adhesion, cell migration, and angiogenesis, to treat conditions related to cell adhesion including endothelial and epithelial cell proliferation, migration, and barrier function, and to identify agents that alter nectin polypeptide activities.

Nectin polypeptides

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Seattle, WA, United States of America

Adel Youakim