Astrazeneca Ab

Novexel

Novexel Sa

Adel Kebsi

Benoit Ledoussal

Camille Pierres

Maxime Lampilas

Marie-Edith Gourdel

Emilie Renaud

David Alan Rowlands

David Alun Rowlands

The invention relates to nitrogenous heterocyclic compounds of formula (I): in which:

Substituted pyrazolo[3,4-E][diazepin-6-5(H)ones and analogues thereof, their preparation and their use as antibacterial medicaments

The invention relates to nitrogen-containing heterocyclic compounds of general formula (I) wherein:Rrepresents a (CH)&#x2014;NHradical, n being equal to 1 or 2;Rrepresents a hydrogen atom;Rand Rform together a nitrogen-containing heterocycle with aromaticity with 5 apices containing 1, 2 or 3 nitrogen atoms, substituted on this nitrogen atom or one of these nitrogen atoms with a (CH)&#x2014;(C(O))&#x2014;Rgroup, m being equal to 0, 1, 2 or 3, p being equal to 0 or 1 and Rrepresenting a hydroxy group, in which case p is equal to 1, or an amino, (C-C)alkyl or di-(C-C)alkyl amino, a nitrogen-containing heterocycle with aromaticity with 5 or 6 apices containing 1 or 2 nitrogen atoms and if necessary, an oxygen or sulfur atom;

Nitrogen-containing heterocyclic compounds, their preparation and their use as antibacterial drugs

The invention concerns nitrogenated heterocyclic compounds, their preparation and use as antibacterial drugs, compounds of general formula (I) wherein Rrepresents a (CH)n-NHRor (CH)n-NHR radical, where R is a (C-C) alkyl and n is equal to 1 or 2;

Nitrogenous heterocyclic compounds, preparation thereof and use thereof as antibacterial medicaments

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Romainville, France

Adel Kebsi