International Business Machines Corporation

Adam Spiro

Chen Yanover

There is provided a method for generating instructions for adjusting a medical treatment of a patient, comprising: detecting an indication of a new symptom appearing in a patient being treated with medications for medical condition(s), computing a value indicative of risk of the new symptom being an adverse drug reaction (ADR) of one or a combination of the medications, detecting an indication of another new medication for treating the patient, computing likelihood of PC when the new medication is for treating the new symptom and the value is according to a requirement, generating a request for substitute medication(s) for the one or combination of medications when likelihood of PC is detected, and generating instructions for adjusting treatment of the patient by substituting the one or combination of medications with the substitute medication(s), and for terminating administration of the new medication or avoiding administration of the new medication.

Systems and methods for adjusting medical treatment to reduce likelihood of prescription cascade

Embodiments of the present systems and methods may provide techniques that provide enrichment of semantic graphing with relations that can enable a higher resolution of the semantic relationships and enable a more accurate prediction of new relations in the graph. For example a method for drug discovery and drug repositioning may comprise generating semantic relationships, at the computer system, based on data relating to a plurality of aspects of drugs and pharmaceutical compounds, generated semantic relationships represented in the form of a semantic graph, learning, at the computer system, new relations among the semantic relationships in the semantic graph using Denoising Autoencoders to process the semantic graph, and generating, at the computer system, predictions for drug discovery and drug repositioning based on the semantic relationships, including the newly found relations.

Growing community of inventors

Tel Aviv, Israel

Adam Spiro