Placon Therapeutics, Inc.

Adam H Brockman

Mark T Bilodeau

Benoît Moreau

Edward R Lee

Rossitza Gueorguieva Alargova

Kristan Meetze

Richard Wooster

Kerry Whalen

The present disclosure relates to novel platinum compositions having a heterocycle ligand and nanoparticles and methods using such compositions, e.g. for treating cancer.

Platinum compounds having a heterocycle ligand, nanoparticles, and uses thereof

The present teachings relate to compounds and compositions for treatment of cancers. In some embodiments, the composition comprises a platinum (IV) complex having at least one reacting group for reacting with a functional group on a protein, engineered protein, antibody, antibody fragment, peptide, agonist, antagonist, aptamer or ligand which may be capable of recognizing a selected target cell population, and/or derivatives/analogs/mimics thereof.

Platinum compounds, compositions, and uses thereof

The present teachings relate to compounds and compositions for treatment of cancers. In some embodiments, the composition comprises a platinum (IV) complex having at least one carboxylate or carbamate ligand.

Compounds, compositions, and methods for the treatment of cancers

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Arlington, MA, United States of America

Adam H Brockman