23andme, Inc.

Adam Auton

Kimberly Faith McManus

Ethan Macneil Jewett

William Allen Freyman

Joanna Louise Mountain

Andrew Seaman

Cordell T Blakkan

Peter Richard Wilton

Susan M Furest

Gabriel David Poznik

Rachel E Lopatin

Hang Xu

Suyash S Shringarpure

Hilary M Vance

Example embodiments relate to identity-by-descent (IBD) relatedness based on focal and reference segments. An example method includes determining, by a services platform based on personal information of a focal individual, a focal string. The method also includes retrieving, by the services platform from a reference database, a reference string of a reference individual. Additionally, the method includes computationally identifying, by the services platform, IBD segments between the focal string and the reference string. Further, the method includes determining, by the services platform and based on the merged set of IBD segments, a degree of relatedness between the focal individual and the reference individual. In addition, the method includes providing, by the services platform, access to the degree of relatedness via a user interface.

Identity-by-descent relatedness based on focal and reference segments

Presenting ancestral origin information, comprising: receiving a request to display ancestry data of an individual; obtaining ancestry composition information of the individual, the ancestry composition information including information pertaining to a proportion of the individual's genotype data that is deemed to correspond to a specific ancestry; and presenting the ancestry composition information to be displayed.

Ancestry composition determination

The disclosed embodiments concern methods, apparatus, systems and computer program products for determining and displaying pedigrees based on IBD data. Some implementations use a probabilistic relationship model to obtain various likelihoods of various potential relationships based on pairwise IBD data and pairwise age data. Some implementations build large pedigrees by combining smaller pedigrees. Some implementations display pedigree graphs with various features that are informative and easy to understand.

Methods and systems for determining and displaying pedigrees

Growing community of inventors

Menlo Park, CA, United States of America

Adam Auton