King Fahd University of Petroleum and Minerals

Adam A A Sulaiman

Anvarhusein Abdulkadir Isab

Muhammad Altaf

Ali Alhoshani

Mohammad Altaf

The invention is directed to a method of treatment of proliferative diseases or disorders such as cancer with gold(I) N-heterocyclic carbene (NHC) thiourea or substituted thiourea complexes, to the complexes per se and to therapeutic compositions containing these gold(I) based complexes.

Method of treating cancer and other proliferative diseases with a gold(I) complex

Gold(I) N-heterocyclic carbene thiourea complex and therapeutic compositions thereof

Method of treating a proliferative disorder by administering a thiourea gold(I) complex

Platinum(II) complexes with various selenones (L) having the general formula PtL(NH)Xare disclosed. The platinum(II) complexes inhibit growth of cancer cells in vitro and are useful for treatment of proliferative disorders such as cancers and/or tumors.

Anticancer trans-diaminoplatinum(II) complexes of selenones

Gold(I)-carbene complexes having a selenium donor ligand with anti-cancer activity and a method of treating cancer. Methods of treating cancer comprising administering the complexes are also provided.

Method for treating cancer using a selenourea-coordinated gold(I)-carbene complex

Gold(I) complexes as antiproliferative or antitumor agents. The gold(I) ion is connected to a N-heterocyclic carbene and further coordinated to a selone ligand. Also described are a pharmaceutical composition incorporating the gold(I) complex, a method of synthesizing the gold(I) complex, and a method for treating a proliferative disorder (e.g. cancer)

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Dhahran, Saudi Arabia

Adam A A Sulaiman