Sanaria Inc.

Abraham G Eappen

Stephen L Hoffman

The application is directed to in vitro-rearedsporozoites of human host range wherein sporogony from gametocyte stage to sporozoite stage is external to mosquitoes, and methods of producing the same. Provided herein are in vitro-reared infectioussporozoites (SPZ) of human host range, particularly, and, wherein sporogony from gametocyte stage to sporozoite stage is external to mosquitoes, and methods of producing the same.

Infectious plasmodium sporozoites grown in vitro

Infectioussporozoites grown in vitro

The application is directed to in-vitro-rearedsporozoites of human host range wherein sporogony from gametocyte stage to sporozoite stage is external to mosquitoes, and methods of producing the same. Provided herein are in vitro-reared infectioussporozoites (SPZ) of human host range, particularly, and, wherein sporogony from gametocyte stage to sporozoite stage is external to mosquitoes, and methods of producing the same.

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Ellicott City, MD, United States of America

Abraham G Eappen