University of Pittsburgh

University of Florida Research Foundation Inc

Other

Abhinav Prakash Acharya

Benjamin George Keselowsky

Steven R Little

Michael J Clare-Salzler

Edward William Scott

Jamal Lewis

Stephen R Little

Emina Huang

Matthew Carstens

Niren Murthy

Elliot C Woods

Tatum Varut Tarin

The present disclosure relates to probiotics and probiotic compositions having modified energy metabolisms (e.g., modifying, metabolizing, or storing energy molecules, e.g., lipids, before the energy molecules are absorbed by a host subject), and thus modulating the absorption of the energy molecules by the host subject. The present disclosure also relates to methods of making such probiotics and probiotic compositions. The present disclosure further relates to methods of regulating (e.g., maintaining or reducing) body weight in a subject (e.g., a subject having a healthy BMI, a subject having an overweight BMI, a subject having an obese BMI), using the probiotics and probiotic compositions disclosed herein.

Probiotics and probiotic compositions for regulating body weight

A Fe(II)- and Ca-chelated alginate/gelatin conjugate.

Assay for detection of bladder or prostate cancer

The present invention provides antigen-specific, tolerance-inducing microparticles for the targeted delivery of therapeutic agents to immune cells. In addition, the present invention allows for sustained release of therapeutic agents for a prolonged period of time. Also provided are therapeutic uses of the present invention for the prevention and/or treatment of immune diseases and autoimmune disorders. In a specific embodiment, the present invention provides treatment for type 1 diabetes.

Antigen-specific, tolerance-inducing microparticles and uses thereof

Stapled acid-sensitive endosome disrupting alginates

The present disclosure provides methods of reducing levels of lactate in a fluid or tissue in an individual. The present disclosure provides pharmaceutical compositions suitable for use in the methods.

Compositions and methods for reducing lactate levels

Embodiments of the present disclosure provide for arrays, systems, and methods analyzing cells, methods of making arrays, and the like.

Cell-based arrays, methods of making, and methods of using

Embodiments of the present disclosure provide for arrays, systems, and methods for the analyzing cells, methods of making arrays, and the like.

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Pitsburgh, PA, United States of America

Abhinav Prakash Acharya