Nalge Nunc International Corporation

Abdul Wahid Khan

Keith Owen Whittlinger

Hoyt E Matthai

Kenneth E Bunn

Kathleen R Williamson

Barbara Myszkiewicz Sullivan

Susan K W Nanda

Erika Lynn Tracy

Susan K Nanda

Wendy Kay Scholz

Margaret Maria Kelly

A method of making a multi-well test plate including an upper frame portion and a glass panel secured to a lower side of the upper frame portion with a layer of light-curable adhesive. The upper frame portion includes a plurality of walls defining adjacent wells for receiving assay samples. The adhesive has various properties, such as high viscosity, thixotropicity, transparency, water insolubility, non-autofluorescence, and non-toxicity, as well as others that are advantageous when constructing and using the multi-well test plate. The adhesive is preferably applied by a screen transfer process that takes advantage of the adhesive properties.

Method of making a multi-well test plate having adhesively secured transparent bottom panel

A multi-slide assembly includes various components that alone or in combination facilitate testing of test samples with minimal manipulation of assay components. Moreover, the various device components permit centrifugation, culturing and analysis of each test sample to be performed in the same assembly. A frame retains a plurality of reaction vessel assemblies between a pair of opposing channels that are configured to slidably receive the opposing ends of each reaction vessel assembly. A strip cap seals the openings in each reaction vessel using cap members having sealing rings circumscribing the external walls thereof to form compression seals with internal walls of the reaction vessels. Furthermore, in a method of making a multi-well slide assembly, an ultrasonic welding process removably bonds a plurality of wells to a slide plate to provide an adequate seal therebetween during centrifugation, yet still enable separation thereof by an operator.

Multi-slide assembly including slide, frame and strip cap, and methods thereof

Multi-slide assembly including slide, frame and strip cap, and methods

Growing community of inventors

Naperville, IL, United States of America

Abdul Wahid Khan