Aventis Pharmaceuticals Inc.

Dupont Pharmaceuticals Company

Abdul Ezaz Mutlib

Soo Sung Ko

Steven P Seitz

Mona Patel

Stephen J Shimshock

Anthony J Cocuzza

Rodney Lawrence Parsons, Jr

David Donald Christ

Jay Andrew Markwalder

Susan M Chesson

This application relates to compounds of the formula ##STR1## wherein R, X and Y are defined within, which compounds are useful for the treatment of memory dysfunction characterized by decreased cholinergic function, and for analgesia, pharmaceutical compositions containing the compounds and methods for making and using the compounds.

Isatin derivatives as acetylcholinesterase inhibitors and analgesics

The present invention relates to benzoxazinones of formula I: ##STR1## or stereoisomeric forms or mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same, methods of using the same for treating viral infection or as an assay standard or reagent, and intermediates and processes for making the same.

4,4-disubstitued-1,4-dihydro-2H-3,1-benzoxazin-2-ones useful as HIV

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Bear, DE, United States of America

Abdul Ezaz Mutlib