Prometic Biosciences Inc.

Abdallah Ezzitouni

Boulos Zacharie

Christopher L Penney

Jean-Simon Duceppe

Lyne Gagnon

Brigitte Grouix

Shaun Abbott

Jean-François Bienvenu

Daniel Fortin

Nicole Wilb

Alan D Cameron

Karine Houde

Nancie Moreau

Shaun D Abbott

A process for the preparation of metal salts of a medium-chain length monocarboxylic fatty acid comprises reacting the precursor free fatty acid, dissolved in a suitable solvent, with the appropriate metal salt. The process uses a relatively high concentration of free fatty acid as a soluble reactant and produces metal fatty acid salts at high purity and high yield at a reasonable cost.

Preparation of metal salts of medium-chain fatty acids

Compounds containing two mono- or disubstituted triazine rings covalently linked by an organic linker, but not linked directly to each other, may be used to treat autoimmune diseases. Autoimmune diseases which are amenable to treatment with compounds of this invention include rheumatoid arthritis, systemic lupus erythematosus (SLE), idiopathic (immune) thrombocytopenia (ITP), glomerulonephritis and vasculitis. The present invention also relates to reducing drug toxicity which often accompanies traditional therapies for autoimmune diseases. The compounds may also be used to bind antibody in vitro or ex vivo.

Triazine dimers for the treatment of autoimmune diseases

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Abdallah Ezzitouni