Redwood Bioscience, Inc.

Plexxikon Inc.

Redwiid Bioscience, Inc.

Redwood Biosciences, Inc.

Aaron Edward Albers

David Rabuka

Romas Alvydas Kudirka

Albert W Garofalo

Robyn M Barfield

Wayne Spevak

Jiazhong Zhang

Guoxian Wu

Phuongly Pham

John Buell

Jesse M McFarland

Hannah Powers

Ying Zhang

Gregory W deHart

Penelope M Drake

Zuojun Guo

Songyuan Shi

Jeffrey Yung Wu

Jack Walleshauser

Prabha N Ibrahim

Jack Lin

Elizabeth A Burton

Jesse M Mcfarland

Gregory W Dehart

The present disclosure provides conjugate structures and hydrazinyl-pyrrolo compound structures used to produce these conjugates. The disclosure also encompasses methods of production of such conjugates, as well as methods of using the same.

Hydrazinyl-pyrrolo compounds and methods for producing a conjugate

The present disclosure provides anti-HER2 antibody-maytansine conjugate structures. The disclosure also encompasses methods of production of such conjugates, as well as methods of using the same.

Anti-HER2 antibody-maytansine conjugates and methods of use thereof

The present disclosure provides conjugate structures (e.g., polypeptide conjugates) and hydrazinyl-indole compounds used to produce these conjugates. The disclosure also provides methods of production of such conjugates, as well as methods of using the same.

Hydrazinyl-indole compounds and methods for producing a conjugate

Disclosed are compounds of Formula (I) and (Ia): 

Compounds and methods for IDO and TDO modulation, and indications therefor

Compounds and methods for CDK8 modulation and indications therefor

Disclosed are compounds of Formula I(a): 

Disclosed are compounds of Formula I(b): or a pharmaceutically acceptable salt, a solvate, a tautomer, an isomer or a deuterated analog thereof, wherein Ring A, Ring HD, J, each T, R, R, R, each R, and m are as described in any of the embodiments described in this disclosure; compositions thereof; and uses thereof.

Compounds and methods for kinase modulation, and indications therefor

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San Francisco, CA, United States of America

Aaron Edward Albers