Makoto Ohki

Title: Makoto Ohki: Innovator in Biochemical Reagents

Introduction

Makoto Ohki is a notable inventor based in Kokubunji, Japan, recognized for his contributions to the field of biochemical reagents. With a total of five patents to his name, he has made significant advancements in the determination of specific biochemical compounds.

Latest Patents

Ohki's latest patents include a reagent for determining (1→3)-β-D-glucan. This invention provides a reagent that comprises a lysate substantially free from any endotoxin-sensitive factor. The lysate is obtained by contacting limulus amebocyte lysate, optionally containing dextran, with a polyamide or cellulose insoluble carrier. This innovation allows for the rapid and accurate determination of (1→3)-β-D-glucan of mycotic origin found in body fluids such as blood or urine. Another significant patent is the horseshoe crab amebocyte lysate factor G activation inhibitor. This invention features a polyglycoside containing at least one poly-(1→3)-β-D-glucoside structure portion, which is useful for inhibiting the activation of factor G in horseshoe crab amebocyte lysate used in the Limulus test.

Career Highlights

Throughout his career, Ohki has worked with prominent companies such as Seikagaku Kogyo Co. Ltd. and Seikagaku Corporation. His work in these organizations has contributed to the development of innovative solutions in the field of biochemistry.

Collaborations

Ohki has collaborated with notable coworkers, including Shigenori Tanaka and Hiroshi Tamura. Their combined expertise has furthered advancements in their respective fields.

Conclusion

Makoto Ohki's contributions to biochemical reagents and his innovative patents highlight his significant role in advancing scientific research. His work continues to impact the field positively.