Joseph L Kukura, Ii

Title: Joseph L Kukura, II: Innovator in Crystallization Processes

Introduction

Joseph L Kukura, II is a notable inventor based in Metuchen, NJ (US). He has made significant contributions to the field of chemistry, particularly in the crystallization of pharmaceutical compounds. His work is essential for the development of effective medications.

Latest Patents

Joseph L Kukura, II holds a patent for a process related to the crystallization of a reverse transcriptase inhibitor. The patent describes a method for crystallizing (-)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one from a solvent and anti-solvent system. This innovative method produces a crystalline product, with the desired final crystal form, Form I, being achievable using methanol or ethanol. Additionally, Form II can be isolated from 2-propanol and converted to the desired crystal form at low drying temperatures, specifically between 40°C and 50°C.

Career Highlights

Joseph L Kukura, II is associated with Merck & Company, Inc., a leading global healthcare company. His work at Merck has allowed him to contribute to advancements in pharmaceutical research and development. His expertise in crystallization processes plays a crucial role in the formulation of new drugs.

Collaborations

One of his notable collaborators is William L Clarke. Their partnership has likely fostered innovative approaches to research and development within their field.

Conclusion

Joseph L Kukura, II is a distinguished inventor whose work in crystallization processes has significant implications for the pharmaceutical industry. His contributions continue to influence the development of effective medications.