Company Filing History:
2 out of 443 
1 out of 112 
Years Active: 2011-2015
Title: The Innovations of Andrew Sprague in Genetic Research
Introduction
Andrew Sprague, an accomplished inventor based in Haverhill, MA, has made significant contributions to the field of genetic research. With two patents to his name, his work focuses predominantly on developing innovative compositions and methods aimed at inhibiting the expression of specific genes, which could lead to advancements in therapeutic treatments.
Latest Patents
Among Andrew Sprague's notable inventions are his patents related to compositions and methods for inhibiting the expression of the IKK-B gene. His work introduces a double-stranded ribonucleic acid (dsRNA) designed to inhibit this gene's expression. The dsRNA comprises an antisense strand with a nucleotide sequence that is less than 30 nucleotides in length, generally ranging from 19 to 25 nucleotides. This strand is substantially complementary to a portion of the IKK-B gene. The invention also details a pharmaceutical composition that includes the dsRNA along with a pharmaceutically acceptable carrier. This composition can be utilized in methods for treating diseases caused by the expression or activation of the IKK-B gene, as well as for inhibiting its expression in cells.
Career Highlights
Throughout his career, Andrew Sprague has been associated with prominent organizations such as Alnylam Pharmaceuticals, Inc. and the Imperial College of Science, Technology and Medicine. His work in these institutions has enabled him to explore groundbreaking concepts in genetic engineering and therapeutic applications.
Collaborations
Collaboration plays a crucial role in scientific innovation, and Andrew has worked alongside esteemed colleagues like Antonin de Fougerolles and Jens Harborth. Their combined expertise and insights have been instrumental in advancing research directions and promoting the development of effective therapies.
Conclusion
Andrew Sprague stands out as a prolific inventor in the domain of genetic research. With a focus on the IKK-B gene, his patented inventions have the potential to transform treatment methodologies for various diseases. As he continues to explore new frontiers in genetic engineering, his contributions will undoubtedly shape the future of medical research and therapy.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.